SCIENTIFIC TIMELINE
ESRF id26 | master thesis
The Electronic Structure of Mn Compounds by Resonant Inelastic X-ray Scattering (RIXS)
My master thesis project is somehow a continue of what I did for previous internship in ESRF. The K pre-edge region for Mn compounds is of interest to study the local geometry and oxidation state. The resonant inelastic x-ray scattering (RIXS) spectra were measured for a series of Mn mononuclear compounds. The resonance occurs when the incident energy is tuned close to an absorption edge, resulting in an energy transfer reduced to a few eV. By interpreting in terms of a second energy transfer axis, one can find new spectral features and this opens up possibilities for more detailed studies of the electronic structure. Data processing was done by using Python programming and simulations were obtained by Quanty package.
03.2017
- 08.2017
I did a lab-work related to electron-beam monitoring in the Munich Compact Light Source (MuCLS). The MuCLS, which has only a room’s size, is based on inverse Compton scattering. By using a small electron storage ring together with a laser-driven optical cavity, it is able to provide undulator-like hard X-rays. The brilliant performance and the comparatively low cost of MuCLS fill the gap between X-ray tube and synchrotrons, opening up the possibility of feasible installation for clinical purpose. The relatively large X-ray beam and quasi-monochromatic feature makes MuCLS a very promising X-ray source for biomedical research and preclinical studies.
The Munich Compact Light Scource (MuCLS)
Simulation of Manganese K-edge and
L-edge X-ray Absorption Spectra
It is a challenging issue to determine the reaction mechanism where the valence of manganese is not straightforward to evaluate with chemistry alone. X-ray absorption spectroscopy (XAS) is an element-specific spectroscopic method that can reflect the electronic structure information of the element. After the absorption of an X-ray photon, a core electron is excited to empty or partially filled orbital which is just below the ionisation threshold, giving an absorption edge. This unique energy provides fingerprint information about the oxidation state, site symmetry, spin state, and crystal field splitting of the targeting materials. The ab initio calculations were carried out by ORCA package during the work to mainly study the spectral changes and electronic transitions.
ESRF id26 | internship
05.2016
- 08.2016
MuCLS
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The electron storage ring and the optical system
Picture from Lyncean. co
09.2014
- 07.2015
Photodynamic Therapy (PDT)
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Photodynamic therapy (PDT) takes advantage of light-activated drugs.
Under two-photon laser irradiation, the photosensitizers are able to ablate key sites such as the mitochondria and the cytomembrane of the HeLa cancer cells.
Two-photon luminescent metal complexes for bioimaging and cancer phototherapy
- 03.2017
12.2016
TUM e17 | internship
I am working on x-ray absorption spectroscopy (XAS) with the MuCLS. Modern XAS is a very powerful technique which is widely used in chemistry, physics, material science and so on. Mostly it is carried out in synchrotrons because of their better performance. With inverse Compton source which has much higher flux and tuneable spectrum, we are working on synchrotron-comparable XAS with a to be used for a wide range of elements.
01.2018
- present
TUM e17 | PhD work
Our groups’ research interest is mainly focused on the applications of two-photon luminescent metal complexes in cell organelles imaging, messenger molecules tracking and cancer therapeutic agents. Two-photon absorption (TPA) and excited emission (TPE) materials has attracted increasing attention due to the advantage of reduced photo-damage and high-resolution 3D structural imaging. And my bachelor thesis was based on Iridium complex for mitochondrial live imaging.
As for cancer therapeutic agents, we are mainly interested in Photodynamic therapy(PDT) with Ruthenium medicinal complex and Photothermal therapy (PTT) with gold nanoparticles or carbon nanotubes. PDT agents act as photosensitizing drugs using light and an adequate concentration of molecular oxygen. PDT harnesses energy from light and damages target tissue by producing cytotoxic species such as singlet oxygen (1O2). Different with PDT, in PTT the photon energy is converted into heat, which destroys the tumour sites. Due to the fundamental specificity and selectivity, the development of PDT/PTT as a therapeutic agent is particularly attractive.
12.2011
- 05.2013
SYSU Lehn Institute | Bachelor internship
Quantum Dot Sensitized Solar Cell (QDSSC)
Quantum dot sensitized solar cells (QDSSC) are the third generation of solar cells. Compared to bulk materials where the bandgap is fixed, the bandgaps of quantum dots are tunable across a wide range of energy levels by changing the quantum dot size. And this makes QDSSC possible to take use of more visible light, thus increasing the photon-to-electron conversion efficiency. In this work, the ZnO nanorods are synthesized on the FTO glass by hydrothermal method and a feasible ion-exchange method is adopted to get a series of different quantum dots. The TEM, STM were carried out to characterize the nano structures. And photovoltaic tests such as I-V curve were measured to identify the performance of the solar cells.
SYSU MOE Key Laboratory | Bachelor thesis